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A Whole New World of Personal Wellbeing

WHAT IS THIS?
Psilocybin is a hallucinogenic chemical in certain mushrooms that grow in Europe, South America, Mexico, and the United States. Mushrooms that contain psilocybin are known as magic mushrooms. 

Individuals use psilocybin as a recreational drug. It can provide feelings of euphoria and sensory distortion that are common to hallucinogenic drugs, such as LSD

Researchers at Johns Hopkins Center for Psychedelic and Consciousness Research published a landmark studyTrusted Source on the safety and positive effects of psilocybin in 2006. Researchers have also investigated whether it may be used to treat various medical conditions. 

In October 2020, Oregon became the first state to

legalize psilocybin. This allows for a 2-year period to

consider regulatory and prescribing requirements.

Psilocybin is a Schedule I substance, meaning that

the Drug Enforcement Administration (DEA)believes

it has a high potential for abuse and serves no

legitimate medical purpose. 

Although medical bodies do not consider

psilocybin addictive, users may experience

disturbing hallucinationsanxiety, and panic 

after taking the drug.

How it works

Psilocybin works by activating serotonin receptors, most often in the prefrontal cortex. This part of the brain affects mood, cognition, and perception. Hallucinogens also work in other regions of the brain that regulate arousal and panic responses.

Psilocybin does not always cause active visual or auditory hallucinations. Instead, it distorts how some people that use the drug perceive objects and people already in their environment.

The quantity of the drug a person consumes, their past experiences, and their expectations of how the experience will take shape can all impact the effects of psilocybin.

The hallucinogenic effects of psilocybin usually occur within 30 minutes after a person ingests it and last 4–6 hours. In some individuals, changes in sensory perception and thought patterns can last for several days.

The potency of a magic mushroom depends on:

  • species

  • origin

  • growing conditions

  • harvest period

  • whether a person eats them fresh or dried

The amount of psilocybin in dried mushrooms is about 10 times higher than that found in their fresh counterparts.

 

Consumption

Mushrooms containing psilocybin are small and usually brown or tan. In the wild, people often mistake mushrooms containing psilocybin for any number of other mushrooms that are poisonous.

People usually consume psilocybin as a brewed tea or prepare it with a food item to mask its bitter taste. Manufacturers also crush dried mushrooms into a powder and prepare them in capsule form. Some people who consume these mushrooms cover them with chocolate.
 

Extent of use

The 2015 National Survey on Drug Use and Health suggested that 8.5% of people in the U.S. had used psilocybin at some point in their life.  The ritual use of psilocybin for mystical or spiritual purposes dates backTrusted Source to pre-Columbian Mesoamerican societies and continues to this day. Psilocybin is often used recreationally at dance clubs or by people seeking a transcendent spiritual experience. 

In medical settings, doctors have tested psilocybin for treating cluster headachesdepression, end stage cancer anxiety, and other forms of anxiety.

Some scientists have questioned its effectiveness and safety as a therapeutic measure.

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